Shandong Shengli Bioengineering Co., Ltd., headquartered in Jining, Shandong Province, is a premier high-tech enterprise specializing in the research, production, and commercialization of veterinary antibiotics and feed additives. As a subsidiary of China National Agricultural Development Group (CNADC), Shengli Bioengineering operates at the forefront of animal health innovation, with a focus on antibiotic active pharmaceutical ingredients (APIs) critical for improving livestock productivity and disease resistance.
Core Business and Product Portfolio
Shengli Bioengineering is recognized for its broad portfolio of veterinary pharmaceutical products, particularly antibiotics used in feed and therapeutic applications. The company offers a mix of ionophores, macrolides, peptide antibiotics, and broad-spectrum antibiotics, covering both growth promotion and disease prevention.
Feed Additive Antibiotics
- Enramycin: Widely used as a non-absorbable antibiotic feed additive targeting Gram-positive bacteria; enhances growth and feed conversion in poultry and swine.
- Bambermycin: Promotes growth by inhibiting Gram-positive bacteria in the digestive tract; allows for higher nutrient absorption.
- Hainanmycin: A unique anticoccidial and antimicrobial agent used in poultry production.
- Nosiheptide: Effective against Clostridium and Staphylococcus; used in feed to reduce enteric infections.
Ionophores and Anticoccidials
- Monensin: Used primarily in ruminants and poultry to control coccidiosis and improve feed efficiency.
- Salinomycin: A highly effective ionophore antibiotic against coccidial species; included in poultry feed for prophylactic purposes.
Veterinary Therapeutic Antibiotics
- Tiamulin Fumarate: Semi-synthetic antibiotic used in the treatment of respiratory and enteric infections in swine and poultry.
- Florfenicol: Broad-spectrum synthetic antibiotic used for bacterial infections in cattle, swine, and aquaculture.
- Tilmicosin: Macrolide class drug used to treat respiratory diseases caused by Pasteurella, Mycoplasma, and other pathogens.
- Doxycycline Hydrochloride: Tetracycline derivative effective against a wide range of bacterial infections in livestock.
Manufacturing Capabilities
Shengli operates GMP-certified production facilities equipped with modern fermentation, extraction, purification, and granulation systems. The facilities are designed for:
- High-volume antibiotic fermentation
- Solvent recovery and purification
- Microbial strain development and culture
- Granular and premix formulations for feed applications
The company’s manufacturing infrastructure allows for both API and finished formulation production, ensuring supply chain control and consistency.
Quality Control and Compliance
All production lines are supported by stringent QA/QC protocols and certified systems:
- GMP Certificate (Veterinary) – Issued by the Ministry of Agriculture and Rural Affairs of China
- ISO 9001:2015 – Quality Management
- ISO 22000 – Food Safety Management (feed-grade products)
- FAMI-QS – For products exported to the EU
- REACH Registration – For selected molecules in compliance with European chemical regulations
Products are subjected to rigorous testing using HPLC, GC, UV-spectrophotometry, and microbial potency assays to ensure purity, activity, and safety.
R&D and Innovation
With a dedicated research center, Shengli Bioengineering focuses on:
- Development of antibiotic alternatives and lower-residue molecules
- Resistance monitoring and mitigation strategies
- Pharmacokinetics and delivery system improvements
- Microbial strain optimization and biosynthesis enhancement
The company collaborates with universities and research institutes and holds multiple invention patents related to fermentation processes and antimicrobial compound production.
Global Market and Export Activity
Shengli Bioengineering maintains a strong international footprint, exporting products to over 40 countries, including:
- Brazil
- Vietnam
- India
- Russia
- Egypt
- Thailand
According to data from global trade intelligence platforms:
- International Shipments (2021–2023): Over 250 verified consignments
- Top Exported Products: Enramycin, Monensin, Florfenicol
- Distribution Channels: Veterinary pharmaceutical manufacturers, feed mill integrators, government tenders
The company participates in international exhibitions such as VIV Asia, IPPE, and CPhI Worldwide, reflecting its commitment to global market development.
Target Clients
- Veterinary pharmaceutical manufacturers and formulators
- Feed additive companies
- Livestock integrators
- Agricultural distributors
- National animal health programs
Shengli’s products are widely adopted in poultry, swine, ruminant, and aquaculture production systems, supporting both growth performance and disease control.
Milestones and Recognitions
- 2022: Expanded production capacity for Florfenicol to meet rising global demand
- 2021: Received Shandong Provincial Enterprise Technology Center status
- 2020: Granted national award for innovation in low-residue antimicrobial agent development
- 2019: Ranked in the top 10 veterinary pharmaceutical exporters in China
With its combination of industrial scale, regulatory compliance, technical expertise, and global reach, Shandong Shengli Bioengineering Co., Ltd. continues to lead the field in veterinary antibiotics and feed additive solutions, enabling safer and more productive livestock farming worldwide.
