Wuhan Grand Hoyo Co., Ltd., headquartered in Wuhan, China, is a leading biopharmaceutical and amino acid manufacturer, specializing in the production of high-purity L-cysteine and its derivatives. With more than two decades of operational experience, the company has earned a global reputation for its advanced fermentation processes and pharmaceutical-grade amino acid products.
Core Business
The core business of Wuhan Grand Hoyo lies in the research, development, manufacturing, and global distribution of amino acids and active pharmaceutical ingredients (APIs). The company is among the earliest in China to industrialize the bio-fermentation production of L-cysteine, and it continues to dominate both the domestic and international markets in this niche.
Product and Service Offerings
Wuhan Grand Hoyo offers a specialized portfolio of amino acids and their derivatives, widely used in pharmaceutical, nutraceutical, cosmetic, and food industries:
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Amino Acids:
- L-Cysteine
- L-Cysteine Hydrochloride Anhydrous
- L-Cysteine Hydrochloride Monohydrate
- Carbocisteine
- N-Acetyl-Cysteine
- N-Acetyl-Tyrosine
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Amino Acid Derivatives:
- Acetylcysteine
- Acetyltyrosine
- Cysteine Hydrochloride
- Arginine Hydrochloride
- Histidine Hydrochloride
- Lysine Hydrochloride
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Active Pharmaceutical Ingredients (APIs):
- Acetylcysteine (used for respiratory and liver treatment drugs)
- Carbocisteine (used as mucolytic agent in respiratory medicines)
These ingredients serve critical roles in antioxidant therapy, liver support, protein synthesis, immune modulation, and flavor enhancement in food processing.
Specialisation and USP
Wuhan Grand Hoyo is globally recognized for its innovation in cysteine-based amino acid fermentation. Its primary strength lies in using non-animal, microbial fermentation technology, making its products suitable for vegan, halal, and kosher applications — a significant USP for global clients in regulated markets.
Key competitive advantages include:
- Industry-leading fermentation and purification processes
- High purity and low endotoxin grade APIs
- Consistent batch production for pharmaceutical standards
- Custom synthesis and contract manufacturing capabilities
Financials
Though precise annual revenue figures are not publicly disclosed, Wuhan Grand Hoyo operates as a high-value export-oriented enterprise. Based on the company’s global presence and production scale, industry estimates place its revenue in the range of USD 40 million to USD 80 million annually.
In 2022, it was listed among Hubei Province’s Top 50 Export Biotech Firms.
Shipment and Export Data
Data from global trade intelligence platforms such as ImportYeti, Volza, and Chinese customs records show:
- Total International Shipments (2020–2023): Over 1,350 shipments
- Top Export Destinations: United States, Germany, Japan, India, Brazil, South Korea
- Key Exported Products: L-Cysteine Hydrochloride Monohydrate, N-Acetyl-Cysteine, Carbocisteine
- Packaging Formats: Bulk API-grade drums and pharma-grade pouches (10–25 kg)
Wuhan Grand Hoyo supplies directly to global pharmaceutical manufacturers and nutraceutical formulation companies, with extensive documentation support for GMP and DMF submissions.
Target Market
The company targets a wide range of industries and clients, including:
- Pharmaceutical companies formulating mucolytic, liver detox, and immune-modulating drugs
- Nutraceutical brands offering antioxidant and amino acid supplements
- Cosmetic brands using amino acids in anti-aging and hydration formulations
- Food and beverage manufacturers incorporating amino acids as enhancers or supplements
Capabilities
Wuhan Grand Hoyo’s manufacturing campus includes:
- GMP-compliant fermentation plants
- Multi-step purification and crystallization systems
- Dedicated API workshops with cleanroom technology
- Advanced QC/QA laboratories equipped with HPLC, GC-MS, and ICP-MS systems
- Research and Innovation Center for amino acid technology
The company maintains full vertical integration, enabling control from microbial strain development to final product packaging.
Certifications and Compliance
The company maintains stringent quality control systems and holds multiple international certifications:
- cGMP (Current Good Manufacturing Practice)
- ISO 9001: Quality Management System
- ISO 14001: Environmental Management System
- Halal Certification
- Kosher Certification
- CEP (Certificate of Suitability) for select APIs
- US DMF (Drug Master File) filings for L-Cysteine and Acetylcysteine
- Chinese FDA registration for pharmaceutical manufacturing
These certifications make Wuhan Grand Hoyo compliant with regulatory bodies such as US FDA, EU EMA, and CFDA.
Customer Testimonials
Although formal testimonials are not published, reviews and case studies on industry procurement platforms note:
- Consistent pharmaceutical-grade quality of L-Cysteine and NAC
- Compliance-ready documentation and regulatory support
- Reliable global shipping and after-sales technical assistance
Major Achievements
- Pioneer of fermentation-based L-Cysteine in China, replacing animal-extraction methods
- Holds multiple patents in amino acid bioengineering
- Recognized as National High-tech Enterprise of China
- Participated in CPhI Worldwide, Vitafoods, and FI Asia as a featured exhibitor
- Expanded annual fermentation capacity to over 1,000 metric tons
With an unwavering commitment to technological excellence and global health compliance, Wuhan Grand Hoyo Co., Ltd. continues to be a dominant supplier of high-value amino acids and APIs worldwide.
