Established in 1561 by apothecary Domenico di Vincenzo di Domenico Brunetti, Farmacia SS. Annunziata 1561 has a rich history of crafting perfumes, cosmetics, and home fragrances. Located in Florence, Italy, the company blends traditional Italian craftsmanship with modern techniques to produce high-quality products. Over the centuries, it has evolved from a medieval apothecary to a renowned brand in the cosmetics and perfumery industry, celebrating its 460th anniversary in 2021 with a special fragrance collection.